The Doctor's Farmacy With Mark Hyman, M.d.

Today we tackle Parkinson’s as a preventable epidemic—not an inevitable fate. I’m joined on The Dr. Hyman Show by two of the field’s top neurologists, Drs. Ray Dorsey and Michael Okun, co-authors of The Parkinson’s Plan, to unpack why cases are exploding and what we can do about it right now. We look at how toxins drive disease, why Parkinson’s goes far beyond dopamine, and the early signs most people miss—plus what you can do today to protect your brain. And we connect the dots between environmental exposures—whether from food, water, or even recreational spaces—and the growing burden of neurological disease. Watch the full conversation here or listen wherever you get your podcasts. [YOUTUBE THUMBNAIL] We also explore: • How to spot early signs—like loss of smell—long before a diagnosis • Everyday ways to cut toxin exposures in your food, water, and home • Why Parkinson’s is a whole-body disease, and what that means for prevention • The kind of exercise that protects your brain and slows progression

Our immune systems are under more pressure than ever—from processed diets, environmental toxins, stress, and fast-spreading infections—and the result is faster aging and greater vulnerability to disease. As we grow older, “zombie cells” spread inflammation throughout the body, weakening defenses and accelerating decline. But research shows we’re not powerless: the emerging science of immuno-rejuvenation reveals that we can retrain and rebuild our immunity. Through the right foods, lifestyle habits, and even strategic stressors, the body has hidden pathways for repair and renewal—offering clues to how we might slow aging and unlock greater resilience. In this episode, I discuss, along with Dr. Elizabeth Boham and Dr. Roger Seheult, how we can support the immune system by using food, lifestyle, and hormetic stress to reduce illness and restore resilience while slowing aging. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Ce

Obesity is often seen as a matter of willpower, but science tells a different story. My guest today, Dr. David Kessler—former FDA commissioner, lawyer, physician, and the man who took on Big Tobacco—explains why biology, not blame, drives our struggles with weight. On this episode of The Dr. Hyman Show, we talk about why weight struggles are so common today, what new drugs can and can’t do, and how his new FDA petition targets one of the biggest culprits: processed refined carbs. Catch the full conversation on YouTube, or listen wherever you get your podcasts. [YOUTUBE THUMBNAIL] You’ll learn: • How food companies use ingredients like processed refined carbs to make products irresistible • Why GLP-1 drugs help many lose weight—but can’t fix the food environment driving the crisis • How belly fat fuels heart disease, diabetes, and cancer—and why ultraprocessed foods are a big part of the problem • Simple ways to break free from foods engineered to make you overeat • What Dr. Kessler’s FDA petition coul

Thyroid trouble often starts as a whisper—tiredness, stubborn weight, dry skin—until a closer look shows the tiny neck gland that sets the body’s “speed” is out of tune. Basic tests can miss the real issue, so checking active hormones and thyroid antibodies—and hunting for triggers like stress, gluten sensitivity, toxins, nutrient gaps, and gut imbalances—can reveal what’s really going on. When understood this way, thyroid health is no longer just about numbers on a lab report—it’s about restoring balance in the whole system. With the right testing, nutrition, and support, energy, mood, and metabolism can all return to their natural rhythm. In this episode, I discuss, along with Dr. Elizabeth Boham and Dr. George Papanicolaou, thyroid conditions such as hypothyroidism, hyperthyroidism, thyroid autoimmunity and how Functional Medicine practitioners take a different approach to find the root cause of the imbalance. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she i

For too long, psychiatry has treated mental illness as if it lives only in the brain. But what if the real story begins in the body? My guest today, Dr. Shebani Sethi, is a Clinical Associate Professor at Stanford and founding director of the Metabolic Psychiatry Program, the first clinic to unite psychiatry with nutrition and metabolism. On this revealing episode of The Dr. Hyman Show, we explore how shifts in metabolism affect the brain and why this whole-body lens could transform how we prevent, understand, and treat mental health. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We discuss: • How to recognize metabolic red flags behind mood and focus • Tests you can ask for to uncover hidden drivers of mental health • Everyday steps to restore brain energy and resilience • Foods and nutrients that calm inflammation and support cognition Dr. Shebani Sethi coined the term Metabolic Psychiatry, capturing what I’ve long believed and explored: that mental health begins i

Many people feel caught in worry, fear, and constant striving—chasing achievements yet never feeling truly fulfilled. The restless “monkey mind” jumps from one thing to the next, amplifying stress and turning setbacks into heavy burdens. It doesn’t have to be that way, though. You can move from mindless tasks to a mindful purpose. The shift begins by setting a clear, heartfelt intention rooted in something bigger. When the focus moves from self-gain to contribution, the right people, resources, and opportunities often begin to flow toward you.  In this episode, Reverend Michael Beckwith, Lynne Twist, Jay Shetty, and I talk about how shifting from fear and self-focus to living with intention, surrender, daily spiritual practices, and a purpose larger than oneself can transform challenges into growth, bring deeper fulfillment, and open unexpected opportunities. For over 30 years now, Reverend Michael Beckwith has embraced a practical approach to spirituality and has helped people see the benefits of meditatio

Most women are told that midlife decline is inevitable—more aches, weaker bones, less strength. But is that really true? On this episode of The Dr. Hyman Show, I sit down with Dr. Vonda Wright, a double-board certified orthopedic surgeon and leading voice in women’s longevity and performance. She shares how muscle functions as medicine, how hormones shape longevity, and why women’s midlife health deserves a whole new conversation. Join us for the full conversation on YouTube, or listen wherever you get your podcasts. What you’ll discover: • How to protect your strength, bones, and independence after 40 • Training shifts that build power, balance, and resilience you can feel every day • Why hormone therapy may be safer and more effective than you’ve been told • Nutrition habits that feed muscle, boost energy, and slow midlife decline • The key tests that reveal your true healthspan—and how to act on them Aging is universal, but frailty is not. With the right focus on strength, hormones, and lifestyle

Many psychiatric labels—like bipolar disorder and schizophrenia—can obscure underlying biology, and symptom checklists often fail to explain or heal what’s really going on. Emerging evidence reframes mental illness as a problem of brain energy, mitochondria, and inflammation—shaped by insulin signaling, circadian rhythm disruption, the gut–brain axis, toxins, infections, and nutrient status. Metabolic interventions such as ketogenic nutrition, already established for epilepsy, show promise for rebalancing neurotransmitters, lowering neuroinflammation, and improving overall brain function. With depression now a leading cause of disability, shifting from “manage the symptoms” to “fix the biology” could dramatically improve outcomes where standard drugs fall short. In this episode, Dr. Christopher Palmer, Dr. Todd LePine, Dr. Iain Campbell and I explore how rethinking mental illness as a metabolic and inflammatory disorder of the brain—rather than just a chemical imbalance—could transform the treatment and prev

On this episode of The Dr. Hyman Show, I sit down with Nick Brewer, founder of Primal Moves—a method born from his own healing journey. Once a pro skier turned drug smuggler, he spent ten years in prison, including four in solitary, where he discovered the power of breath and movement to rebuild his body and mind. I had the chance to try Nick’s class myself, and I was struck by how powerful such simple movements can be. I’m excited to share that experience with you. You can watch the full conversation on YouTube, or listen wherever you get your podcasts. [YOUTUBE THUMBNAIL] We discuss: • How to spot when your nervous system is stuck—and steps to restore balance • Why talk therapy alone can’t release trauma in the body • How group movement triggers natural feel-good brain chemistry • Why we feel cut off from our bodies and how to reconnect Healing starts in the body. By working through stress and pain, we gain the strength and energy to show up fully in life. My hope is that this conversation encourage

Inflammation is the body’s natural way of healing, but when it becomes chronic and hidden, it quietly drives many of today’s most common health problems—heart disease, diabetes, dementia, cancer, autoimmune conditions, and more. Unlike the redness and swelling from a cut or sprain, this “silent inflammation” often goes unnoticed while slowly damaging tissues and speeding up aging. Modern life fuels the fire: processed foods, food additives, pollution, plastics, chronic stress, too much sitting, and poor sleep. The good news is inflammation can be calmed by simple daily choices—eating colorful whole foods like berries, leafy greens, beans, nuts, seeds, and omega-3 rich fish; adding herbs and spices like turmeric and cumin; moving regularly; practicing relaxation; and repairing gut health. Even small shifts, like climbing stairs, eating within a shorter window, or reducing sugar, can make a big difference. By lowering inflammation, the body finds balance again, opening the door to more energy, resilience, and h

For decades, psychiatry has relied on treatments that are slow and often ineffective. But what if one intervention could reset the brain, break the grip of addiction, and open the door to an entirely new model of care? On this episode of The Dr. Hyman Show, I sit down with Dr. Nolan Williams, a Stanford neuropsychiatrist pioneering new therapies for substance use disorders, depression, PTSD, and traumatic brain injury. We dive into these fascinating topics and more; watch the full conversation on YouTube or listen wherever you get your podcasts. You’ll learn: • Why ibogaine is unlike any other psychedelic—and how it could reset the brain • Its promise for treating substance abuse disorders and breaking cycles of addiction • The safety step that makes ibogaine treatment possible for real patients • Why psychiatry is shifting from trial-and-error to targeted brain circuits Talks like this remind me just how close we are to real breakthroughs in mental health. Dr. Williams calls it psychiatry 3.0. It’s a

Nutrients are far more than supplements on a shelf—they are life-sustaining molecules that determine how well the body ages and resists disease. For years, their importance was overlooked because many studies were poorly designed, failing to consider existing nutrient levels or how vitamins and minerals work together. Strong evidence now shows multivitamins can slow brain aging, omega-3s can extend life expectancy, and shortages of vitamin D, magnesium, and B12 are widespread drivers of inflammation and chronic illness. Knowing and addressing individual deficiencies is critical, as these nutrients power billions of chemical reactions every second and are foundational to vitality and longevity. In this episode, I discuss, along with Dr. Rhonda Patrick and Steve Martocci, why nutrients are essential for a healthy body and how to choose the highest quality supplements. Dr. Rhonda Patrick is a scientist and health educator recognized for her leadership in aging and disease prevention. As the founder of FoundMyF

It’s been five years since Ben Greenfield joined me on The Dr. Hyman Show, and a lot has changed. Ben isn’t doing many of the things he once swore by. In fact, he’s discovered that some of the most powerful practices for health and longevity are simpler and more sustainable than the extreme routines he became known for.  In this episode, we talk about the biohacks he’s left behind, the innovations he still uses, and the deeper priorities that now guide his life. Join us on YouTube for the full talk or listen wherever you get your podcasts. [YOUTUBE THUMBNAIL] We discuss: • How much exercise is truly healthy, and when it starts working against you • Simple training shifts that build strength and stamina while protecting long-term health • What recovery tools can actually speed healing and reduce inflammation • Can light and oxygen really reset your body’s rhythms and improve sleep? • Why community, family, and spiritual health may be the most overlooked keys to longevity True longevity isn’t found in

As women enter perimenopause and menopause, hormonal shifts—declining estrogen, progesterone, and testosterone—can ripple through nearly every system in the body, impacting bone density, cardiovascular health, metabolism, brain function, and sexual wellbeing. Misinterpretation of past research left millions fearful of hormone therapy, yet newer evidence shows that bioidentical hormones, started within a specific “window of opportunity,” can protect the heart, brain, bones, and quality of life. Supporting this transition in a woman’s life also means addressing nutrition, gut health, stress, sleep, and strength training—powerful tools that work alongside hormones to restore vitality. With the right knowledge and care, this phase of life can be transformational, leading to renewal, resilience, and long-term health protection. In this episode, I explore, along with Dr. Mary Claire Haver and Dr. Cindy Geyer, how we can shift our thinking of peri-menopause and menopause to one of renewed health and vitality. Mary

In a world where healthcare often focuses on treating illness rather than promoting wellness, what does it really take to live a healthy, vibrant life? In this episode of The Dr. Hyman Show, I sit down with John Mackey, co-founder of Whole Foods Market, to explore his journey from building one of America’s most iconic food companies to rethinking health, purpose, and consciousness. We talk about his new venture, Love.Life, and how it fits into a bigger philosophy that includes conscious capitalism and living with meaning. You can catch our full conversation on YouTube or listen wherever you get your podcasts. We unpack: • What psychedelic insights can teach you about health and consciousness • How conscious capitalism can create “win-win-win” outcomes in your life • Steps you can take to break free from habits driving weight gain and poor health • Why building the right community accelerates your health journey • What living with purpose can do for your well-being at every stage of life This conv

Relationships have the power to change lives in ways both visible and hidden. Deep, supportive bonds can quiet inflammation in the body, protect against disease, and anchor people through decades of triumphs and trials. Communities that come together—whether in small groups at a church or around a shared health goal—often achieve far more than individuals working alone, sometimes transforming their health on a massive scale. Lifelong friends celebrate each other’s victories without jealousy, weather hardship side by side, and dare to speak difficult truths even at the risk of the relationship. Yet, many remain in unfulfilling connections out of fear of loneliness, forgetting that genuine, vulnerable connection is not just emotionally nourishing—it is essential to human health and resilience. In this episode, I talk with Simon Sinek, Esther Perel, and Angelika Alana about how relationships are vital not just for emotional health, but for physical wellbeing and can be a great source of growth and healing. Sim

With so much conflicting health advice online, it’s no wonder people feel overwhelmed by food choices. Is saturated fat really the enemy? Are seed oils as harmful as some headlines claim? And how do we know what’s actually true?  In this episode of The Dr. Hyman Show, I sit down with nutrition researcher and author Simon Hill to make sense of the latest science and help you cut through the confusion. You can watch our full conversation on YouTube or listen wherever you get your podcasts. We discuss: • The real story behind seed oils, saturated fat, and inflammation—and what to do about it • What your lab work can tell you about your unique nutrition needs • How to spot nutrition misinformation and think critically about food trends • Why cutting back on ultra-processed foods may be more important than obsessing over any single nutrient In a world full of nutrition noise, this episode helps you tune into what really matters—science, and your own body. View Show Notes From This Episode Get Free Weekl

Medicine stands at the threshold of a new era, where artificial intelligence and systems biology are working hand in hand to make care more personal, predictive, and precise than ever before. AI is already improving diagnostic accuracy, automating administrative tasks, and uncovering patterns in data—like retinal scans or genomics—that humans often miss. Rather than replacing doctors, AI enhances their ability to deliver more informed, precise, and efficient care. At the same time, individuals are gaining tools—from at-home diagnostics to wearable biosensors—that empower them to track and optimize their own health. This shift marks a move from reactive, disease-centered care to a proactive, data-driven model of scientific wellness. In this episode, I talk with Dr. Eric Topol, Dr. Nathan Price, Dr. Leroy Hood, Dr. Vijay Pande, and Daisy Wolf about how artificial intelligence, personalized data, and wearable technology are converging to radically transform medicine. Dr. Eric Topol is Executive Vic

This special bonus episode features Dr. Todd LePine from the UltraWellness Center, diving into how functional medicine can help reverse fatty liver disease—an often-overlooked condition that’s quietly affecting millions. While conventional care may miss early warning signs or focus solely on medication, Dr. LePine and I take a deeper look at the root causes. We also walk through a real patient case that shows how liver fat can be reduced and overall health restored through personalized nutrition and lifestyle changes. If you or someone you know has ever been told their liver enzymes are “a little high,” this is a conversation you won’t want to miss. You’ll learn: • Why you could have fatty liver disease—even if you're not overweight or drinking • What elevated liver enzymes really mean for your long-term health • How to protect your liver by cutting out hidden sources of sugar and toxins • Which foods and supplements support detox, reduce inflammation, and repair damage • What a real-life recovery look

Our healthcare system is broken—and it’s not by accident. On this episode of The Dr. Hyman Show, I’m joined by Brigham Buhler, a former pharmaceutical rep turned healthcare entrepreneur, to explore how misaligned incentives across pharma, insurance, and government are undermining patient care.  This conversation is about more than just exposing the problem. It’s about empowering individuals. Watch our full discussion on my YouTube channel here - https://youtu.be/062lululORA We discuss: • How hidden financial incentives could be affecting the care you receive • Why even well-meaning doctors may be limited in helping you heal—and what you can do about it • What to watch out for when navigating insurance, prescriptions, and denied claims • How you can prioritize prevention, even when it’s not supported Navigating the healthcare system can be overwhelming, but your next step doesn’t have to be. With the right insight, you can take back control and advocate for the care you deserve. View Show Notes From T