Sinopsis
You have wisely landed upon Authentic Biochemistry, with Dr Daniel J Guerra, where published research and clinical science is interrogated.
Episodios
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The hormonal and allosteric control over hepatic PFK2/FBPase2 via adenylate cyclase and Fructose 2,6 bis phosphate. DJGPhD.5Sept.2021. Authentic Biochemistry Productions.
05/09/2021 Duración: 30minDr. Guerra details the glucagon and epinephrine mediated control through Stimulatory G-protein couple adenylate cyclase activating PKA over Hepatic Glycolysis and Gluconeogenesis. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Glycerol 3-phosphate dehydrogenase mechanism and the finale of glycolysis. Authentic Biochemistry. Dr. Daniel J. Guerra 27.8.21
27/08/2021 Duración: 29minUtilization of a protein cysteine SH derived thioester intermediate alters the free energy hurdle for the synthesis of 1,3 bis PGA thus allowing for glycolytic ATP and NADH synthesis. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Haemoglobin: Molecular Oxygen Binding Cooperativity and the role of 2,3 bis phosphoglyceric acid. DJGPhD 19.8.21
20/08/2021 Duración: 29minThe interaction of glycolysis and lactic acid transport from skeletal muscle to the liver plays a significant role in oxygen uptake, transport and release in association with pulmonary carbon dioxide efflux . Dr. Daniel J. Guerra. An Authentic Biochemistry Production 19.8.21. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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A Necessary Interruption in Amino Acid Catabolism: Haemoglobin and Oxygen Transport Lecture I. DJGPhD. 11 August 2021
11/08/2021 Duración: 29minAny chronic decrease in the ability for molecular oxygen to bind to circulating Hb will diminish its availability in the Central Nervous System and Skeletal Muscle resulting in the potential for long-term Pathophysiology and Illness. Dr. Dan Guerra Published 11 August 2021. Authentic Biochemistry. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Amino Acid Catabolism (Continued): Neurotransmitter and S-adenosyl MET interconversions. DJGPhD 09 Aug 2021
09/08/2021 Duración: 24minClassical Amino Acid Degradation Biochemistry : Emphasis on pathway interconversions and production of bioactive amines --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Main Frame Amino Acid Degradation Pathways and Skeletal Muscle Performance and Ammonia Toxicity.02.Aug.2021. DJGPhD. Authentic Biochemistry
02/08/2021 Duración: 30minJ Physiol. 2005 563:285-90 Eur J Appl Physiol(2011) 111:2837–2843 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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The Urea Cycle and the endothelial ARGININE-Nitric Oxide Connection. DJGPhD 27.7.21.Authentic Biochemistry Podcast
27/07/2021 Duración: 29minBiomedicines. 2020 Aug 6;8(8):277. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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The Glutamate Dehydrogenase Axis Further Reveals the Role of Ischaemic Oxygen Availability for Neural Transmission in the Aging Brain. DJGPhD 20.7.21.
20/07/2021 Duración: 29minJournal of Neurochemistry, Volume: 146, Issue: 4, Pages: 416-428, First published: 20 May 2018, DOI: (10.1111/jnc.14464 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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The Glutamate Axis of Bioenergetics, Neurotransmission and Potential Contribution to the Aging Senescent Phenotype. DJGPhD 20.7.21
20/07/2021 Duración: 29minJournal of Neurochemistry, Volume: 146, Issue: 4, Pages: 416-428, First published: 20 May 2018, DOI: (10.1111/jnc.14464) Life Sci . 2019 Sep 1;232:116612 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Amino acid metabolism I: An initial primer for subsequent discussions in Aging. Dr Guerra. 07July2021. Authentic Biochemistry.
12/07/2021 Duración: 29minThis is one of my classical biochemistry introductory lectures on amino acid utilization. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Mesenchymal stem cell fate and the mediation of age-associated senescence or plasticity in the elderly via immune response valency. DJGPhD 03 July 2021
04/07/2021 Duración: 27minTrends in Immunology Volume 36, Issue 4, 2015, 217–228 Carcinogenesis 2015;36:1180-1192 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Detailing the Senescent to Mesenchymal Transition in Aging : Links to Cancer vs. Apoptosis. DJGPhD 28 June 2021.
28/06/2021 Duración: 29minClinical and Molecular Allergy volume 15, Article number: 21 (2017) Front. Immunol., 25 September 2019 | https://doi.org/10.3389/fimmu.2019.02247 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Genomic damage, DDR, and the roles of inflammation and DNA epigenetic retailoring in the senescent phenotype. DJGPhD 24.6.21
25/06/2021 Duración: 29minOncotarget. 2013 Oct; 4(10): 1552–1553 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Pharmacodynamics: General Considerations and Clinical Trials. Dr. Dan Guerra. Authentic Biochemistry 12 June 2021
12/06/2021 Duración: 29minIn this episode Dr. Guerra provides the overview of Pharmacodynamics . --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Pharmacokinetics Synoptic with an Introduction to Aging Phenomena. Dr Daniel J. Guerra. 09June2021 authentic Biochemistry.
10/06/2021 Duración: 29minA.D.M.E. Anesthesiology Clinics, 2019-09-01, Volume 37, Issue 3, Pages 475-492. Please subscribe and donate! Dr. Guerra needs your support! --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Cardiovascular disease risk and malnutrition are associated with aging morbidity and obesity. Dr. Guerra. 8 June 2021. Authentic Biochemistry
08/06/2021 Duración: 28minRisk factors for aging morbidity are linked to large variations in protein synthesis and lack of adipose derived TAG utilization. The immune response becomes compromised during aging leading to states of hyperinflammation followed by hypo-immune sequalae opening up the potential for opportunistic respiratory infections and alterations in pulmonary endothelial membrane lipid fluidity restricting oxygen intake. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Ceramide mediated pathophysiology of aging-associated neurodegeneration. Dr. Dan Guerra. Authentic Biochemistry.05 June 2021.
05/06/2021 Duración: 28minSeminars in Cell & Developmental Biology Volume 40, April 2015, Pages 115-126 Pharmaceutical Research March 2018, 35:49 Journal of Molecular Endocrinology 2017. 58, 1; 10.1530/JME-16-0182 J. Lipid Res. 2018 59:(3) 488-506. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Immuno Endocrine Regulation of Metabolism May-June 2021. Dr. Dan Guerra Authentic Biochemistry.
03/06/2021 Duración: 29minFeng, T., Yang, X., Hao, S. et al. Immunol Res. 05 April 2020 Molecular Neurodegeneration volume 7, Article number: 45 (2012) J Biol Chem. 2019 Jun 7;294(23):9213-9224 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Aging and Cancer Via Immunosenescence and Pro-inflammatory Cytokines: Relative loss of Naive T cell Populations in the Elderly. DJGPhD. 26 March 2021
26/05/2021 Duración: 29minAnnu. Rev. Physiol. 2013. 75:685–705 Nutrients. 2020 Mar; 12(3): 622 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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Pathobiochemical linkages between Alzheimer's Disease and Autism Spectrum Disorders: Associative Molecular Patterns with Diverse Pathologies. DJGPhD. 18 May 2021
19/05/2021 Duración: 29minFASEB J. 2013 Jun; 27(6): 2458–2467. Scientific Reports volume 7, Article number: 13763 (2017) --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message