Sinopsis
You have wisely landed upon Authentic Biochemistry, with Dr Daniel J Guerra, where published research and clinical science is interrogated.
Episodios
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![Authentic Biochemistry is moving to a remote geographical region but will do so seamlessly and with full dedication. Please SUBSCRIBE and take notice of the discussion I have recorded here. DJGPhD]()
Authentic Biochemistry is moving to a remote geographical region but will do so seamlessly and with full dedication. Please SUBSCRIBE and take notice of the discussion I have recorded here. DJGPhD
20/04/2022 Duración: 29minDr Guerra takes this episode to redouble the committment of Authentic Biochemistry to providea detailed analysis and synthesis of current biomedical research science based on peer-reviewed published literature. Please become a regular subscriber! Grazie! --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXXVI. Coda. Final lecture in diabetic dyslipidaemia.]()
Diabetes XXXVI. Coda. Final lecture in diabetic dyslipidaemia.
20/04/2022 Duración: 29minReferences Dr. Guerra lipid lectures Journal of Diabetes Research, 2016, Article ID 2372741, 12 pages Lipids in Health and Disease 2013.12(1):98 Cell Reports 2022. 38, 110566 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXXV. Rodent model adipose mitochondrial respiratory contribution to obesity control involves a selenium protein and UCP1 sulfenylation. Dr Daniel J. Guerra. Authentic Biochemistry.18.4.22]()
Diabetes XXXV. Rodent model adipose mitochondrial respiratory contribution to obesity control involves a selenium protein and UCP1 sulfenylation. Dr Daniel J. Guerra. Authentic Biochemistry.18.4.22
19/04/2022 Duración: 29minReferences Dr. Guerra Lipid and Intermediary Metabolism lectures Cell Reports 2022. 38, 110566 PNAS July 24, 2017 | 114 (32) 8649-8654 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXXIV. White vs brown adipocytes and the role of transcription factors and metabolic enzyme expression to mediate bioenergetics vs.lipogenesis in store depot fat.DJGPhD.17.4.22. Authentic B.]()
Diabetes XXXIV. White vs brown adipocytes and the role of transcription factors and metabolic enzyme expression to mediate bioenergetics vs.lipogenesis in store depot fat.DJGPhD.17.4.22. Authentic B.
18/04/2022 Duración: 30minReferences Dr. Guerra's lipid lecture archives PNAS July 24, 2017 | 114 (32) 8649-8654 Int J Mol Sci. 2019 Oct; 20(19): 4924 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXXIII. Synthesis of lecture arc Part 2. Dr Daniel J. Guerra. Authentic Biochemistry Podcast Studios. 16.4.22]()
Diabetes XXXIII. Synthesis of lecture arc Part 2. Dr Daniel J. Guerra. Authentic Biochemistry Podcast Studios. 16.4.22
16/04/2022 Duración: 29minReferences Dr. Guerra's notes --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXXII. Fatty acid oxygenation and use of eicosanoid molecular species to regulate T2D-linked inflammation via the agonization of the nuclear receptor transcription factor PPAR.DJGPhD 15.4.22]()
Diabetes XXXII. Fatty acid oxygenation and use of eicosanoid molecular species to regulate T2D-linked inflammation via the agonization of the nuclear receptor transcription factor PPAR.DJGPhD 15.4.22
15/04/2022 Duración: 29minReferences Dr Guerra lipid lecture notes Biophysical J. Volume 110, Issue 11, 7 June 2016, Pages 2397-2406 Am J Pathol. 2020 Sep; 190(9): 1782–1788 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXXI. REDOX biochemistry mini-review and the roles of essential fatty acid elongation/desaturation metabolism and COX/LOX oxygenation as ligands for PPAR isoforms in T2D pharmacotherapy.]()
Diabetes XXXI. REDOX biochemistry mini-review and the roles of essential fatty acid elongation/desaturation metabolism and COX/LOX oxygenation as ligands for PPAR isoforms in T2D pharmacotherapy.
14/04/2022 Duración: 29minReferences Dr. Guerra lecture material Nutr J. 2014; 13: 17. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXX. The pleitropic roles of free fatty acids and PPARs as mediating insulin sensitivity, intermediary metabolism and the inflammatory response in T2D.Dr Daniel J. Guerra 13.4.22. Authentic]()
Diabetes XXX. The pleitropic roles of free fatty acids and PPAR's as mediating insulin sensitivity, intermediary metabolism and the inflammatory response in T2D.Dr Daniel J. Guerra 13.4.22. Authentic
13/04/2022 Duración: 29minReferences Dr. Guerra lecture notes Prog Neurobiol. 2018 Apr-May; 163-164: 27–58. Arteriosclerosis, Thrombosis, and Vascular Biology. 2006;26:28–40 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![DiabetesXXIX. THe CNS axis of Obesity-linked T2D via alterations in PPAR transcription factor mediated expression of ameliorative hippocampal AMPAR and LTP neural transmission in Alzheimers Discsease]()
DiabetesXXIX. THe CNS axis of Obesity-linked T2D via alterations in PPAR transcription factor mediated expression of ameliorative hippocampal AMPAR and LTP neural transmission in Alzheimer's Discsease
12/04/2022 Duración: 29minReferences Dr. Guerra's Lecture Notes Journal of the American College of Nutrition. 2019. 38:8, 693-702. Curr Diabetes Rev. 2020;16(8):797-806 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXVIII. Diabetic nephropathy is a consequence of non-esterified free fatty acid associated ceramide induction of the IRS-1 phosphorylation in glomerular podocytes inducing inflammation]()
Diabetes XXVIII. Diabetic nephropathy is a consequence of non-esterified free fatty acid associated ceramide induction of the IRS-1 phosphorylation in glomerular podocytes inducing inflammation
08/04/2022 Duración: 30minReferences Dr Guerra lecture notes Front. Endocrinol., 14 October 2014. Sci Rep. 2020; 10: 21628. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXVII. Dyslipidaemia and the Insulin Resistance Axis. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast 7April2022.]()
Diabetes XXVII. Dyslipidaemia and the Insulin Resistance Axis. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast 7April2022.
07/04/2022 Duración: 29minReferences Dr. Guerra's lectures Curr Med Chem. 2017;24(17):1827-1852 Cancer Res. 2018 Apr 1; 78(7): 1713–1725 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXVI. Adipogenic and hypertrophic adiposity differentially control dyslipidaemia and Insulin resistance in association with pro-inflammatory cytokine induced T2D and breast cancer.DJGPhD.]()
Diabetes XXVI. Adipogenic and hypertrophic adiposity differentially control dyslipidaemia and Insulin resistance in association with pro-inflammatory cytokine induced T2D and breast cancer.DJGPhD.
05/04/2022 Duración: 29minReferences Dr. Guerra's lipid lecture notes Cancer Res. 2018 Apr 1; 78(7): 1713–1725. Progress in Lipid Research Volume 74, April 2019, Pages 145-159 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXIV. Sphingosine 1-phosphate targeting and the abalation of primary breast cancer metastasis: IL6 mediated tumorigenesis blockade? Dr Daniel J. Guerra 01April2022. Authentic Bbiochemistry]()
Diabetes XXIV. Sphingosine 1-phosphate targeting and the abalation of primary breast cancer metastasis: IL6 mediated tumorigenesis blockade? Dr Daniel J. Guerra 01April2022. Authentic Bbiochemistry
02/04/2022 Duración: 29minReferences Dr Guerra's notes Front. Physiol., 30 January 2019 | https://doi.org/10.3389/fphys.2019.00042 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXIII. Obesity-associated IL6 and sphingosine 1-phosphate are linked to breast cancer.Dr. Daniel J. Guerra. 31 March 2022. Authentic Biochemstry]()
Diabetes XXIII. Obesity-associated IL6 and sphingosine 1-phosphate are linked to breast cancer.Dr. Daniel J. Guerra. 31 March 2022. Authentic Biochemstry
01/04/2022 Duración: 29minReferences Dr. Guerra's lecture notes Front. Physiol., 30 January 2019 | https://doi.org/10.3389/fphys.2019.00042 Cold Spring Harb PerspectBiol. 2018 Feb; 10(2): a028415. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXII. Obesity and cancer are linked by inflammation and dyslipidaemia. Dr Daniel J. Guerra. 30.3.22 Authentic Biochemistry]()
Diabetes XXII. Obesity and cancer are linked by inflammation and dyslipidaemia. Dr Daniel J. Guerra. 30.3.22 Authentic Biochemistry
31/03/2022 Duración: 29minReferences Dr Guerra's lectures notes Cancer Res. 2018 Apr 1; 78(7): 1713–1725 Cold Spring Harb PerspectBiol. 2018 Feb; 10(2): a028415. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XXI. TAG accumulation in skeletal muscle of diabetics vs athletes and suggested role of Intramuscular TAG in Insulin Resistance due to subcelluar localization of lipid droplets. DJGPhD.27.3]()
Diabetes XXI. TAG accumulation in skeletal muscle of diabetics vs athletes and suggested role of Intramuscular TAG in Insulin Resistance due to subcelluar localization of lipid droplets. DJGPhD.27.3
28/03/2022 Duración: 29minReferences Dr Guerra's lecture notes Diabetologia. 2021 Jan; 64(1): 168–180 Diabetologia. 2020 Dec;63(12):2654-2664 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XX. Intermediary metabolic allosteric regulation in the Myocardial Infarcted heart reveals HF aetiology from obesity-linked Type 2 Diabetes. DJGPhD.25.3.22. Authentic Biochemistry Production]()
Diabetes XX. Intermediary metabolic allosteric regulation in the Myocardial Infarcted heart reveals HF aetiology from obesity-linked Type 2 Diabetes. DJGPhD.25.3.22. Authentic Biochemistry Production
25/03/2022 Duración: 29minReferences Dr. Guerra lecture notes J AM Coll Cardiology Basic Trans Science.2019. (4) 3: 385-400 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XIX. THe ketogenesis bioenergetic system can be corrupted via DAG-kinase mediated pyroptosis in the obese/T2D CNS. Dr. Dan Guerra. 22.3.22. Authentic Biochemistry Podcast]()
Diabetes XIX. THe ketogenesis bioenergetic system can be corrupted via DAG-kinase mediated pyroptosis in the obese/T2D CNS. Dr. Dan Guerra. 22.3.22. Authentic Biochemistry Podcast
22/03/2022 Duración: 29minReferences Dr. Guerra lecture notes Circulation Research Volume 128, Issue 10, 14 May 2021; Pages 1419-1420 Adv Exp Med Biol . 2017;960:135-160. Current Opinion in Clinical Nutrition and Metabolic Care Issue: Volume 21(4), July 2018, p 260-266 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XVIII. Myokine mediated muscle mass signaling is corrupted by obesity linked Type 2 diabetes via massive inflammation and dyslipidaemia.DJGPhD. 21.3.22. Authentic Biochemistry]()
Diabetes XVIII. Myokine mediated muscle mass signaling is corrupted by obesity linked Type 2 diabetes via massive inflammation and dyslipidaemia.DJGPhD. 21.3.22. Authentic Biochemistry
21/03/2022 Duración: 29minReferences Dr. Guerra's lecture notes J Immunol. 2018 Nov 15;201(10):2934-2946 Endocr Rev. 2020 Aug; 41(4): 594–609. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Diabetes XVII. Short and medium chain fatty acid derived ketones and skeletal muscle Myokines to improve cognitive and homeostatic well-being in humans. DJGPhD. 20.3.22 Authentic Biochemistry.]()
Diabetes XVII. Short and medium chain fatty acid derived ketones and skeletal muscle Myokines to improve cognitive and homeostatic well-being in humans. DJGPhD. 20.3.22 Authentic Biochemistry.
21/03/2022 Duración: 29minReferences Dr Guerra lecture notes Endocr Rev. 2020 Aug; 41(4): 594–609 Alzheimer’s & Dementia: Translational Research & Clinical Interventions (TRCI) 2021 Volume7, Issue1 e12217 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
