Sinopsis
You have wisely landed upon Authentic Biochemistry, with Dr Daniel J Guerra, where published research and clinical science is interrogated.
Episodios
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![CytoEpigenetics XVIII. Membrane lipid architectonics organized for cell cycle and both nuclear and mitochondrial biochemical mediation of gene expression. Dr. Dan Guerra. 05 June 2022]()
CytoEpigenetics XVIII. Membrane lipid architectonics organized for cell cycle and both nuclear and mitochondrial biochemical mediation of gene expression. Dr. Dan Guerra. 05 June 2022
05/06/2022 Duración: 20minReferences Dr Guerra's synthesis of lecture material Histochemistry and Cell Biology volume 145, pages275–286 (2016) Biol Rev Camb PhilosSoc.. 2018 May;93(2):827-844. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics XVII. The role of ceramide metabolism in epigenetic and bioenergetic cross talk among multiple subcellular compartments. Dr Dan Guerra. 03June2022 Authentic Biochemistry Podcast]()
CytoEpigenetics XVII. The role of ceramide metabolism in epigenetic and bioenergetic cross talk among multiple subcellular compartments. Dr Dan Guerra. 03June2022 Authentic Biochemistry Podcast
04/06/2022 Duración: 29minReferences Dr Guerra's synthesis of lectures Scientific Reports volume 5, Article number: 15292 (2015) --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics XVI. The Mt DNA replicase and helicase enzymes are epigenetically nuclear encoded and localize to the mitochondrial membrane into lipid rafts containing cholesterol. DJGPhD. 2June2022]()
CytoEpigenetics XVI. The Mt DNA replicase and helicase enzymes are epigenetically nuclear encoded and localize to the mitochondrial membrane into lipid rafts containing cholesterol. DJGPhD. 2June2022
02/06/2022 Duración: 29minReferences Dr Guerra's lecture sytheses Scientific Reports volume 5, Article number: 15292 (2015) --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics XV.An AMPK phosphorylation cascade promoting mTOR pro-translational induction of NFkappa-B SASP transcription is modulated by NAD+ Sirtuin and PARP during Chromatin retailoring.DJGPhD]()
CytoEpigenetics XV.An AMPK phosphorylation cascade promoting mTOR pro-translational induction of NFkappa-B SASP transcription is modulated by NAD+ Sirtuin and PARP during Chromatin retailoring.DJGPhD
28/05/2022 Duración: 29minReferences Dr Guerra's synthesis of the relevant literature BioEssays, Volume: 39, Issue: 5, First published: 20 February 2017. Front Cardiovasc Med. 2020; 7: 2. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics XIV. The details of AMPK mediated control over DNA methyl transferase thus coordinating bioenergetics with cell fate via the epitranscriptome. DJGPhD. 25.5.22]()
CytoEpigenetics XIV. The details of AMPK mediated control over DNA methyl transferase thus coordinating bioenergetics with cell fate via the epitranscriptome. DJGPhD. 25.5.22
26/05/2022 Duración: 29minReferences Dr. Guerra's synthesis of the epitranscriptome lecture notes Sci Signal. 2017 Jan 31; 10(464): eaaf7478. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigeneticsXIII. Epitranscriptomics of Fatty acid Utilization is a driver of Heart-Failure associated Cardiorenal disease. Dr daniel J. Guerra. Authentic Biochemistry.22.5.22]()
CytoEpigeneticsXIII. Epitranscriptomics of Fatty acid Utilization is a driver of Heart-Failure associated Cardiorenal disease. Dr daniel J. Guerra. Authentic Biochemistry.22.5.22
22/05/2022 Duración: 29minReferences Sci Signal. 2017 Jan 31; 10(464): eaaf7478 Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55 Nat Commun. 2020; 11: 4664. Int J Biol Sci. 2015; 11(11): 1272–1280 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics XII. The central role of mitochondria in regulating cell fate and metabolic switching is necessary and universal in epigenetic modification of gene expression. DJGPhD.20.5.22]()
CytoEpigenetics XII. The central role of mitochondria in regulating cell fate and metabolic switching is necessary and universal in epigenetic modification of gene expression. DJGPhD.20.5.22
21/05/2022 Duración: 30minReferences Dr Guerra's lecture notations and synthesis Cell. 2014 Dec 18; 159(7): 1615–1625 Nat Commun. 2020; 11: 102. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics XI. The interactive intermediary metabolic architectonic of methylation and acetylation in epigenetic mediation of gene expression between the mitochondria and nucleus. DJGPhD.17.5.22]()
CytoEpigenetics XI. The interactive intermediary metabolic architectonic of methylation and acetylation in epigenetic mediation of gene expression between the mitochondria and nucleus. DJGPhD.17.5.22
18/05/2022 Duración: 29minReferences Dr Guerra's lecture notes Nat Commun. 2020; 11: 102. Cold Spring Harb Perspect Biol. 2013 Sep; 5(9): a017947. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics X. The IDH isofrom roles of mutant, hypoxic and constitutive activities mediate DNA, RNA and Histone3 Lys methylation patterns thus redirecting gene expression.DJGPhD.15.5.22]()
CytoEpigenetics X. The IDH isofrom roles of mutant, hypoxic and constitutive activities mediate DNA, RNA and Histone3 Lys methylation patterns thus redirecting gene expression.DJGPhD.15.5.22
16/05/2022 Duración: 29minReferences Dr Guerra's letures/reasoning SCIENCE ADVANCES • 22 May 2019 • Vol 5, Issue 5 Cell MetabolismVolume 22, Issue 2, 4 August 2015, Pages 304-311 Cell Chem Biol. 2020 May 21; 27(5): 538–550.e7. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Cytoepigenetics IX. c-MYC controls transcription of two dehydrogenases that alter the ratio of 2-HG/alphaKG thus controling epigenetic signatures on DNA and RNA in a cancer mouse model.DJGPhD.11May22]()
Cytoepigenetics IX. c-MYC controls transcription of two dehydrogenases that alter the ratio of 2-HG/alphaKG thus controling epigenetic signatures on DNA and RNA in a cancer mouse model.DJGPhD.11May22
12/05/2022 Duración: 29minReferences Dr Guerra's Lecture notes Cell Chem Biol. 2020 May 21; 27(5): 538–550.e7 Circulation. 2020 Dec 15;142(24):2356-2370 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics VIII. The epigenetic processors, TET and BRD4, mediate control over fatty acid oxidation, pyruvate metabolism, the electron tranport chain and OXPHOS. DJGPhD.8May22. Authentic Biochem]()
CytoEpigenetics VIII. The epigenetic processors, TET and BRD4, mediate control over fatty acid oxidation, pyruvate metabolism, the electron tranport chain and OXPHOS. DJGPhD.8May22. Authentic Biochem
09/05/2022 Duración: 25minReferences Dr Guerra's notes Circulation. 2020 Dec 15;142(24):2356-2370 Cancer Science June 2014. 105(9) --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Cytoepigenetics VIIB. Warburg glycolysis explained from an epigenetic perspective plus some details of DNA methylation/demethylation. DJGPhD. Authentic Biochemistry Podcast 06May2022]()
Cytoepigenetics VIIB. Warburg glycolysis explained from an epigenetic perspective plus some details of DNA methylation/demethylation. DJGPhD. Authentic Biochemistry Podcast 06May2022
07/05/2022 Duración: 29minReferences Dr. Guerra's notes Cancer Res. 2011 May 1; 71(9): 3400–3409 Front. Neurosci., 17 May 2017 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Cytoepigenetics VIIa. Micro RNA control over the electron transport chain and oxidative phosphorylation via binding to nuclear and mitochondrial transcripts. DJGPhD03.may 2022. Authentic Biochemistry]()
Cytoepigenetics VIIa. Micro RNA control over the electron transport chain and oxidative phosphorylation via binding to nuclear and mitochondrial transcripts. DJGPhD03.may 2022. Authentic Biochemistry
04/05/2022 Duración: 21minReferences Dr Guerra's pathbiochemistry lecture notes Cancer Res. 2011 May 1; 71(9): 3400–3409 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics V!. The magmatic alteration of nuclear and mitochondrial gene expression via microRNA processing and translocalization is under bioenergetic control. DJGPhD. 2 May 2022.]()
CytoEpigenetics V!. The 'magmatic' alteration of nuclear and mitochondrial gene expression via microRNA processing and translocalization is under bioenergetic control. DJGPhD. 2 May 2022.
03/05/2022 Duración: 29minReferences Radiol Oncol. 2021 Dec; 55(4): 379–392 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Cytoepigenetics V. Small interfering and micro RNA mediate mitochondrial and nuclear transcripts thus rendering cell fate, bioenergetics, and immunogenicity. DJGPhD.29.4.22. Authentic Biochemsitry]()
Cytoepigenetics V. Small interfering and micro RNA mediate mitochondrial and nuclear transcripts thus rendering cell fate, bioenergetics, and immunogenicity. DJGPhD.29.4.22. Authentic Biochemsitry
29/04/2022 Duración: 29minReferences Guerra lecture notes/ideas Genes (Basel). 2014 Dec; 5(4): 865–886. Molecular Therapy—Nucleic Acids (2015) 4, e252 Int. J. Mol. Sci. 2016, 17(5), 719 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Cytoepigenetics IV. Using Raman and IR spectroscopy to analyze the physical chemistry of pyrimidine nucleotide methylation. Dr. Daniel J. Guerra. 26.4.22. Authentic Biochemistry Podcast Productions]()
Cytoepigenetics IV. Using Raman and IR spectroscopy to analyze the physical chemistry of pyrimidine nucleotide methylation. Dr. Daniel J. Guerra. 26.4.22. Authentic Biochemistry Podcast Productions
26/04/2022 Duración: 29minReferences J of Computational Chemistry 2011 Volume32, Issue10: Pages 2077-2083 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Cytoepigenetics IIIB. The Geometrical constraints decribed by the valence shell electron pair repulsion in biochemical reactivity. DJGPhD.25.4.22]()
Cytoepigenetics IIIB. The Geometrical constraints decribed by the valence shell electron pair repulsion in biochemical reactivity. DJGPhD.25.4.22
25/04/2022 Duración: 27minDr Guerra organic chemistry notes and concepts --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Cytoepigenetics IIIA. Dissection of the PPAR-gamma epigenetic retailoring. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 25.4.2022]()
Cytoepigenetics IIIA. Dissection of the PPAR-gamma epigenetic retailoring. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 25.4.2022
25/04/2022 Duración: 15minReview mini lecture --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Cytoepigenetics II. The First Principle of Biochemical Epigenetics and the dialectic of methylated promoter region PPAR-gamma and peroxisomal mitigation between rodent and human. DJGPhD.24.4.22]()
Cytoepigenetics II. The First Principle of Biochemical Epigenetics and the dialectic of methylated promoter region PPAR-gamma and peroxisomal mitigation between rodent and human. DJGPhD.24.4.22
25/04/2022 Duración: 29minReferences Dr Guerra's ideas and concepts Cells. 2021 Jun; 10(6): 1355. Cells. 2019 Mar; 8(3): 227. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![CytoEpigenetics I. Introduction. Dr. Daniel J. Guerra . 22.4.22. Authentic Biochemistry Podcast Productions]()
CytoEpigenetics I. Introduction. Dr. Daniel J. Guerra . 22.4.22. Authentic Biochemistry Podcast Productions
23/04/2022 Duración: 29minReferences Introductory remarks from Guerra's research Trends in Cell Biology, 2017-06-01, Volume 27, Issue 6, Pages 453-463. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
