Physionic

In this episode, we will be diving extensively into a powerful muscle promoting mechanism known as phospholipase. Following that, we dive into a potential treatment for cancer using an unlikely ally. Finally, I discuss research out of McMaster University developing a new style of antibiotic. Phospholipase (1:18) https://www.youtube.com/watch?v=EtV3yWw0hz8&t=3s Cancer & Unlikely Ally (19:20) Xue Zhang, Tingting Zhang, John N. Davis, Andrea Marzi, Anthony M. Marchese, Michael D. Robek, Anthony N. van den Pol. Mucin-like domain of Ebola virus glycoprotein enhances selective oncolytic actions against brain tumors. Journal of Virology, 2020; DOI: 10.1128/JVI.01967-19 Antibiotic: (25:15) https://www.sciencedaily.com/releases/2020/02/200212131523.htm  

In this podcast, I admittedly nerd out a bit on genetics and how our cells repair our genes when exposed to mutagens (things that cause mutations). However, with good reason, because a new paper has added some clarity to a part of the process and man is it cool! Beyond that, we will go into heart rate variability, as well as if caffeine is associated with migraines? Check it out and share! Rad DNA Repair, 1:03 Roxanne Oshidari, Richard Huang, Maryam Medghalchi, Elizabeth Y. W. Tse, Nasser Ashgriz, Hyun O. Lee, Haley Wyatt, Karim Mekhail. DNA repair by Rad52 liquid droplets. Nature Communications, 2020; 11 (1) DOI: 10.1038/s41467-020-14546-z Heart Rate Variability, 26:20 Giorgio Quer, Pishoy Gouda, Michael Galarnyk, Eric J. Topol, Steven R. Steinhubl. Inter- and intraindividual variability in daily resting heart rate and its associations with age, sex, sleep, BMI, and time of year: Retrospective, longitudinal cohort study of 92,457 adults. PLOS ONE, 2020; 15 (2): e0227709 DOI: 10.1371/journal.pone.0227709

In this episode, we'll be discussing four topics: 1:47 - Coronavirus 14:46 - Contraceptive Technology 22:36 - Marijuana & Birth 28:08 - Sleep Deprivation & Hunger YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this week's episode, we will be discussing many subjects ranging from sudden meat allergies, how asthma presents itself (cellularly), to different "styles" of aging known as ageotypes, as well as even more! Topics and time stamps listed here: Meat Allergy (2:37): https://www.jimmunol.org/content/203/4/813 Selective Asthma (10:50): https://www.nature.com/articles/s41590-019-0496-9 Skin Pain Sensation (19:38): https://science.sciencemag.org/content/365/6454/695 Ageotypes (26:10): https://www.nature.com/articles/s41591-019-0719-5 Protein on Health (31:42): https://www.physionic.org/highproteinonhealth

In this episode, we will go over three articles describing the affect genetics play on cardiovascular disease, as well as sleep's mitigating role. We will also discuss how non-HDL cholesterol affects heart disease risk. Finally, we briefly discuss a study on extreme sugar consumption and its impact on male fertility. (2:28) Genetics & Sleep: Mengyu Fan, Dianjianyi Sun, Tao Zhou, Yoriko Heianza, Jun Lv, Liming Li, Lu Qi. Sleep patterns, genetic susceptibility, and incident cardiovascular disease: a prospective study of 385 292 UK biobank participants. European Heart Journal, 2019; DOI: 10.1093/eurheartj/ehz849 (11:32) Non-HDL Cholesterol: Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. The Lancet, 2019; DOI: 10.1016/S0140-6736(19)32519-X (24:00) Sugar on Fertility: Daniel Nätt, Unn Kugelberg, Eduard Casas, Elizabeth Nedstrand, Stefan Zalavary, Pontus Henriksson, Carola Nijm, Julia Jäderquist, Joha

In this episode, we take a deeper look at a recent video I released on YouTube wherein I describe 5 immutable "laws" of health. Then, we will discuss two bits on cancer research - one wonderful and one interesting. Finally, we finish off with a discussion of "does creatine increase muscle mass directly?" 6:18 - 5 Laws of Health 22:12 - War on Cancer 30:00 - Ketones and Breast Cancer 40:47 - Creatine direct affect on Muscle Hypertrophy? Ketones on Cancer: https://www.physionic.org/overexpressingketonesonbreastcancer 5 Laws of Health: https://www.youtube.com/watch?v=US684eYHLMY&t=1s

This week's episode is an intriguing one as it involves an in-depth dive into the condition known as endometriosis. I am joined by Alyssa Dotson, who had endometriosis and spent several years reading up on the condition. We dive into treatment, diagnosis, her story, what endometriosis is, as well as a study that claims to have found the cause of endometriosis pain, as well as much more. Time Stamps: What is Endometriosis? (2:02) What causes Endometriosis? (3:08) Signs & Symptoms? (6:49) How long has Endometriosis been around, clinically? (19:37) Treatments for Endometriosis? (20:58) Does Endometriosis worsen? (28:35) When should you see a doctor? (30:11) Being your own advocate with your doctor? (31:29) Are there proven tests to diagnose Endometriosis? (33:05) How prevalent is Endometriosis? (35:05) When does Endometriosis occur in life? (36:06) What causes the pain associated with Endometriosis [STUDY] (38:37) Alyssa's IG: @alyssamckenzie Nancy's Nook: https://www.facebook.com/groups/NancysNookEndoE

In this episode, you will hear a little bit on how dogs may have an effect in regards to mental health, how the body uses a particular reaction to control blood pH (acidity and alkalinity), how sleep impacts our food choices (or, the lack thereof), and more. Check it out! 3:29 - Dogs 12:09 - Blood pH 27:32 - Sleep & Food Choice 34:49 - Calorie Deficit & Lifespan Reference: Robert Yolken, Cassie Stallings, Andrea Origoni, Emily Katsafanas, Kevin Sweeney, Amalia Squire, Faith Dickerson. Exposure to household pet cats and dogs in childhood and risk of subsequent diagnosis of schizophrenia or bipolar disorder. PLOS ONE, 2019; 14 (12): e0225320 DOI: 10.1371/journal.pone.0225320

In this episode, we dive into how infrared sauna therapy may or may not be beneficial for endothelial function/heart disease. Study, Notes, & Amendments: https://www.physionic.org/infraredsaunaforheartdisease YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, I discuss why it is imperative to start your exercise life early in this particular regard - your bones. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, I describe a few different mechanisms for why our skin ages through the discovered differences between elderly skin and young skin. Study, Notes, & Amendments: https://www.physionic.org/collagenproductioninagedskin YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, I discuss some research wherein scientists have gotten some clues between autophagy and longer life based on a protein called p62. Reference: Caroline Kumsta, Jessica T. Chang, Reina Lee, Ee Phie Tan, Yongzhi Yang, Rute Loureiro, Elizabeth H. Choy, Shaun H. Y. Lim, Isabel Saez, Alexander Springhorn, Thorsten Hoppe, David Vilchez, Malene Hansen. The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy. Nature Communications, 2019; 10 (1) DOI: 10.1038/s41467-019-13540-4 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, I describe a positive mutation that occurs in some people leading them to have enhanced cognitive ability and longer life. Study, Notes, & Amendments: https://www.physionic.org/klothooncognition YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, we dive into dietary cholesterol and its impact on the body as it relates to increasing serum/blood cholesterol levels. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, I take some time and explain what I've discovered in my reading of many studies on the topic and tracing the possible reasons for differences in libido and sexual function with fat loss. Article, Video, and References: https://www.physionic.org/fatlossandsexdrive [Video will be live at 11am ET today] YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, I discuss the longest heart attack in Spanish history and how a woman SURVIVED after being "dead" for 6 hours. Not only that, I discuss research investigating the retooling of the mammalian brain network under new circumstances. Heart Attack (1:14): https://www.bbc.com/news/uk-50681489 Brain Sensing (8:42): Krystyna Solarana, Ji Liu, Zac Bowen, Hey-Kyoung Lee, Patrick O. Kanold. Temporary visual deprivation causes decorrelation of spatio-temporal population responses in adult mouse auditory cortex. eNeuro, 2019; ENEURO.0269-19.2019 DOI: 10.1523/ENEURO.0269-19.2019 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, I go through a dialogue I wrtoe some time ago discussing the physiology and implications of the "sunshine vitamin" (Vitamin D). YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, I briefly discuss one tiny piece of high impact data wherein diabetes risk is completely eliminated by curcumin supplementation. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this episode, we will go into a bit of detail on metabolism and why it likely does not REALLY slow with age all that much. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

In this brief episode, I discuss a paper wherein the researchers discover that multiple tumors will share, or "cross pollinate" or "self-seed" themselves by sharing cancerous cells. Study, Notes: https://www.physionic.org/cancerselfseeding YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0