Journal Of Investigative Dermatology

19 December 2012: Audio abstracts from the November 2012 JID, including validation of a dermatitis assessment tool, predicting skin cancer in high-risk patients, and a search for new genes and protein expression in psoriasis.

20 December 2012: Audio abstracts from the December 2012 JID, including the role of epigenetics in hair follicle regeneration, the link between alcohol and skin cancer, and a protein that provides immunity against a parasitic disease.

04 January 2013: Join presenter Dr. Jeffrey Dunn as he speaks with Dr. Ruby Ghadially about the past 25 years of epidermal stem cell research. Understanding of epidermal stem cell biology has evolved rapidly as techniques to visualize distribution of stem cells and progeny have improved. However, significant challenges remain, including defining molecular markers for stem cells, determining the locations and contributions of different stem cell niches, and mapping regulatory pathways of epidermal stem cell proliferation and differentiation.

15 January 2013: Join presenter Dr. Robert Dellavalle as he speaks with Dr. John J. DiGiovanna and Dr. Kenneth H. Kraemer from the National Institutes of Health (NIH) about xeroderma pigmentosum (XP), a defect in DNA repair pathways that is characterized by sun sensitivity and UV radiation-induced skin and mucous membrane cancers.

29 January 2013: Join presenter Dr. Robert Dellavalle as he speaks with Dr. Julie Ryan from the University of Rochester Medical Center about ionizing radiation. Although a common treatment for cancer, ionizing radiation can potentially damage skin. There is currently no effective method to prevent skin injury due to radiation exposure; however, knowledge regarding mechanisms of and treatment for radiation dermatitis is improving.

31 January 2013: Audio abstracts from the January 2013 JID, including targets for treating alopecia, a pathway that regulates the hair follicle cycle, and a protein's role in the skin discoloration of melasma.

04 February 2013: Audio abstracts from the February 2013 JID, including the role of vitamin A in alopecia, global incidence and prevalence of psoriasis, and the anti-aging effects of broadband light therapy.

12 February 2013: Join presenter Dr. Robert Dellavalle as he speaks with Dr. Lowell A. Goldsmith, Editor Emeritus of theJID, about the past and future of the Society for Investigative Dermatology (SID). After 75 years, the SID has evolved from its modest beginnings as a society of 300 members to a diverse international organization. To ensure its future, the SID must continue to incorporate new scientific concepts and technologies to facilitate ongoing, vibrant discussion among its members.

14 February 2013: Audio abstracts from the March 2013 JID, including the genetics of a chronic inflammatory skin condition, activation of cells in aged human skin, and a promising combination therapy for melanoma.

19 February 2013: In this podcast, Corinna Wu speaks with Dr. John Parrish, professor of dermatology at Harvard Medical School and director of CIMIT, the Center for the Integration of Medicine and Innovative Technology in Boston, about his recent JID Commentary on translational research.

26 February 2013: Join presenter Dr. Robert Dellavalle as he speaks with Dr. John R. Stanley from the University of Pennsylvania about desmoglein as a target for pemphigus and other skin disease therapies, which has illuminated the pathophysiology of seemingly unrelated diseases.

12 March 2013: In this podcast, Dr. Robert Dellavalle speaks with Dr. Stuart Yuspa, from the National Institutes of Health, about signaling in the skin. Unraveling signaling cascades that transmit information from the cell surface to the nucleus has ushered in a multitude of new therapeutics that targets these pathways.

14 March 2013: Audio abstracts from the April 2013 JID, including a signal that initiates hair follicle development, the link between acne medication and inflammatory bowel disease, and an engineered measles virus that attacks melanoma cells.

26 March 2013: In this podcast, Emilee Sandsmark speaks with Dr. Melody Eide, from the Henry Ford Hospital in Detroit, about the exclusion of non-melanoma skin cancer from US cancer registries, which inspired Dr. Eide to review billing claims and their correspondence to the language of actual pathology records. Electronic pathology reports provide accurate diagnosis, suggesting that their inclusion in a national database would improve understanding of the prevalence, diagnostics, and treatment of squamous and basal cell skin cancer.

03 April 2013: Audio abstracts from the May 2013 JID, including a comparison of treatments for nonmelanoma skin cancers, the use of nanoparticles to treat acne, and new targets for managing melanoma metastasis.

11 April 2013: In this Skinpod episode, Dr. Robert Dellavalle speaks with Dr. Joel Gelfand, from the University of Pennsylvania, about the prevalence of metabolic syndrome in patients in the United Kingdom. This survey is part of a large prospective study that shows the association of psoriasis with cardiovascular events and demonstrates that psoriasis severity is an independent predictor of metabolic syndrome markers, including serum triglyceride and glucose levels.

23 April 2013: Join Dr. Robert Dellavalle as he speaks with Dr. Victoria Werth, from the University of Pennsylvania, about the evaluation of the reliability, validity, and responsiveness of the CDASI and the CAT-BM. Validated diseases severity tools for dermatomyositis (DM) in skin are lacking, and this study demonstrates the usefulness of these tools for intra- and inter-rater reliability with a group of 14 DM patients.

26 April 2013: In this podcast, Dr. Robert Dellavalle speaks with Dr. Victoria Werth about increased mucin in patients with dermatomyositis and how this relates to increased accumulation of a sugar chondroitin sulfate, CD44 Variant 7 and Osteopontin. This clinical finding has been modeled in in vitro experiments of stretched fibroblasts and provides an example of how the immune system can trigger a chronic inflammatory response in the skin.

14 May 2013: In this podcast, Dr. Jeffrey Dunn speaks with Dr. Jared Jagdeo about the effects of light emitting diode (LED) low level light therapy (LLLT) on human skin.

16 May 2013: In this podcast, Dr. Jeffrey Dunn speaks with Dr. Jared Jagdeo about how immunohistochemical staining patterns aid in our understanding of the role of oxidative damage in photoaging.