Throwback Thursday With Dr. Fred Silva

This episode, Dr. Silva discusses the evolution of membranous glomerulopathy detailing the advent of the Jones silver stain and the more recent recognition of underlying pathoetiologic mechanisms of primary disease.

On this episode of Throwback Thursday, Dr. Silva discusses the early classifications of kidney disease and the origins of our current nomenclature.

This week Dr. Silva discusses the history of complement.

This week Dr. Silva relays a personal story of Dr. Paul Kimmelstiel and discusses his contributions to renal pathology and medicine.

This week Dr. Silva finishes his two-part series on the history of nephrology.

In this episode, Dr. Silva gives a brief history of nephrology, including the first kidney transplant.

Join us this week as Dr. Silva discusses the shrouded history of the development of the light microscope.

This week, Dr. Silva discusses minimal change disease, FSGS, and the controversy surrounding these two, potentially linked diseases. 

A tale of two glomerulopathies: For this episode of Throwback Thursday, Dr. Silva discusses the origins of IgA nephropathy and IgM nephropathy.

Even those gifted with a silver tongue have a slip up now and again. In this episode of TBT we take a look at Dr. Silva’s tongue-twisting moments of 2017!

The final portion of the nephron is the collecting duct/tubule and was discovered by Drs. Bellini and Borelli.

The loops of the nephron between the proximal and distal convoluted tubules are often called “The Loops of Henle” after the discoverer of this important part of the kidney.

The relationship of the glomerulus (Malpighian Corpuscle) and the beginning of the proximal tubule was unknown until this investigator discovered what is now called “Bowman’s Capsule."

The first portion of the nephron has in the past been called “The Malpighian Corpuscle” after the individual that discovered it (now called the glomerulus). Here's a blog post on Malpighi: https://www.arkanalabs.com/malpighi-glomerulus/ 

In this episode, Dr. Silva discusses the origins and controversies surrounding ANCA-mediated vasculitis. Note: Dr. Charles Jennette relays that at the ASN meeting in which Fokko Van Der Woude described his discovery of anti-neutrophil antibodies in Wegener's granulomatosis, Dr. Jennette was headed for the same microphone to point out that David Davies had already published this, but David got there first. 

Dr. Silva discusses the history of IgA nephropathy and Jean Berger.

Flank pain, mesangial alteration, and hematuria. What we know and what we don’t.

Did you know tubuloreticular inclusions aren’t specific to lupus? Dr. Silva explains their fascinating history in this episode of TBT.

In this episode, Dr. Silva shares the history of the mesangial cell. A cell type that was hotly contested throughout much of the early 20th century.

In this episode, Dr. Silva discusses the etiology and initial controversies surrounding thin GBM disease.