Dr. Howard Smith Oncall

Vidcast:  https://www.instagram.com/p/DQdlztLFFi-/The hot flashes and night sweats of menopause create a miserable midlife for so many women.  Hormones do offer relief, but many women cannot take them.  Enter a new non-hormonal drug just approved by the FDA.This medication, elinzanetant to be marketed as Lynkuet by Bayer, GlaxoSmithKline, and Nerre Therapeutics, is an oral neurokinin/tachykinin antagonist that normalizes thermal and sleep regulation.  A phase 3 multi-national study headed by researchers at the University of Virginia School of Medicine shows that 120 mg elinzanetant taken daily relieves both the frequency and intensity of hot flashes, improves sleep quality, and elevates moods. Improvement occurred for some study participants within the first week of therapy.Last year, the FDA approved another Bayer oral menopause drug fezolinetant, branded as Veozah. With one neurokinin receptor blocker, it reduces hot flashes only. This year’s new entry is more powerful as it blocks two neurokinin receptors