Bulletproof Radio

Most people track glucose or ketones, but almost no one is measuring the hidden signal that could be silently wrecking your metabolism, brain function, and longevity: uric acid. This episode reveals why this overlooked biomarker drives obesity, diabetes, cardiovascular disease, Alzheimer’s, and even accelerated aging—and how you can hack it to unlock resilience, human performance, and smarter not harder health upgrades. Watch the podcast on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR We revisit host Dave Asprey sitting down with Dr. David Perlmutter, one of the world’s leading functional medicine neurologists and the #1 New York Times bestselling author of Grain Brain and Drop Acid. Dr. Perlmutter has spent decades connecting gut health, brain optimization, and neuroplasticity with lifestyle interventions that truly change the trajectory of disease. In this conversation, he explains how uric acid acts as a metabolic switch that determines whether you burn fat o