Berkeley Talks

For UC Berkeley’s Jennifer Doudna, the revolutionary discovery of CRISPR-Cas9 gene editing began 15 years ago with a meeting at the campus’s Free Speech Movement Cafe. “This is a quintessential story about Berkeley,” begins Doudna, a professor of molecular and cell biology and of chemistry, in a lecture she gave on campus in April. “The research that I'll talk about today wouldn't have happened … if I had been working anywhere else. And that's because we have a really collaborative environment on our campus.”At the cafe, Doudna listened while a Berkeley colleague described a possible adaptive immune system in bacteria that helps them fight off viral infection. Doudna's lab went on to research the molecules involved, discovering a pathway that allows bacteria to "learn" about viruses, store the information and use it for protection.The scientists realized this same system could be used to trigger DNA repair in plant, animal and human cells, effectively allowing them to "rewrite the code of life." The