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Summary - Like a bonzai tree there are times when the brain is developing and malleable. - The brain begins development in the first trimester and continues until age 24. - During adolescence different parts of the brain develop at different times (different branches of the tree) - An insult to the immature brain can cause much more dramatic changes because of its malleability (sapling vs. hardened branch) - All drugs appear to alter parts of the brain associated with learning, memory, emotion regulation, planning and problem solving and impulse control. Learn more about your ad choices. Visit megaphone.fm/adchoices