Peerview Clinical Pharmacology Cme/cne/cpe Audio Podcast

Go online to PeerView.com/FCW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in hepatology provides practical guidance across the spectrum of care from screening and diagnosis to management of patients with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Upon completion of this activity, participants should be better able to: Discuss the epidemiology and disease burden of NAFLD/NASH, Describe the relationship between NAFLD/NASH and cardiovascular disease, Assess current and emerging treatments for NASH in the context of mechanism of action (eg, ability to target various metabolic, inflammatory, and fibrotic pathways involved in disease progression) and current clinical evidence (eg, impact on fibrosis and cardiovascular risk; safety)

Go online to PeerView.com/KZA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. A multidisciplinary panel of experts discuss the expanding role of neuroimaging in the diagnosis and management of Alzheimer’s disease. Upon completion of this CE activity, participants will be able to: Assess the relative utility of the structural, functional, and molecular neuroimaging techniques used in AD diagnosis and management, Implement an evidence-based, guideline-directed approach to using neuroimaging to assess amyloid burden when confirming a diagnosis of AD or determining patient eligibility for use of amyloid-lowering therapy, Apply validated neuroimaging techniques and biomarkers to monitor for treatment response, disease progression, and ARIA or other adverse events in patients being treated for AD, Employ a patient-centered, multidisciplinary approach to patient care in AD

Go online to PeerView.com/DMP860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in hypereosinophilic syndrome discusses the burden, symptoms, and differential diagnosis of the disease, as well as the latest data on treatment. Upon completion of this CE activity, participants will be able to: Describe the burden of hypereosinophilic syndrome (HES) on patients, including the consequences of underdiagnosed and undertreated HES, Explain the role of eosinophils in the pathophysiology of HES, Identify features of HES that differentiate the diagnosis from other eosinophilic disorders, Develop treatment plans for patients with HES based on subtype and the latest clinical evidence.

Go online to PeerView.com/UVR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Understanding practical considerations with systemic therapy in tenosynovial giant cell tumor (TGCT) can be critical for safe delivery of therapy. In this activity, an expert medical oncologist provides a practical update on targeted treatment options for TGCT management, with a focus on safe delivery of care—including appropriate dosing, food effects, and safety considerations—based on the current clinical experience with approved CSF1R inhibitors. Upon completion of this CE activity, participants will be able to: Manage safety and dosing considerations with targeted agents in the setting of TGCT.

Go online to PeerView.com/CPH860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. While TKIs have been a mainstay in the first three lines of treatment for patients with gastrointestinal stromal tumors (GISTs), new discoveries and emerging science have led to the development of newer agents that address treatment resistance. Known as modern TKIs, these agents have a confirmed role in the treatment of patients with specific mutations or in later-line settings and are now being tested in earlier-stage disease. While oncologists, oncology nurses, and other members of the interdisciplinary cancer care team have new opportunities for increasing survival and improving QOL in their patients with unresectable/metastatic GIST, they are also faced with more complex treatment paradigms that must account for mutation profiling, treatment selection/sequencing, symptom and AE management, psychological support, and nutritional considerations. Join our experts to hear how a

Go online to PeerView.com/JUV860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in psychiatry discusses new and emerging therapies addressing unmet patient needs in the management of schizophrenia and bipolar disorder. Upon completion of this activity, participants should be better able to: Describe the barriers and challenges associated with the treatment of patients with schizophrenia and bipolar disorder, Assess the mechanisms of action, efficacy, safety, and tolerability profiles of available and emerging therapies for the management of schizophrenia and bipolar disorder, Incorporate shared decision-making between the interprofessional healthcare team and patients in the individualized management of schizophrenia and bipolar disorder to maximize treatment and mitigate adverse events and disease relapse.

Go online to PeerView.com/HYJ860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Antibodies have allowed clinicians to bring their “A” game when managing multiple myeloma (MM). To see how this happened, watch this activity, developed in collaboration with HealthTree Foundation, to view how experts have rapidly integrated CD38, SLAMF7, and BCMA antibodies into the management of newly diagnosed and relapsed/refractory disease. Each case-based lecture also includes a video testimonial from a patient with MM on how treatment with novel antibodies has made a difference in their lives. Upon completion of this CE activity, participants will be able to: Cite updated evidence on the use of novel antibody platforms targeting CD38, SLAMF7, and BCMA in NDMM and RRMM, Integrate antibody-based therapies, including triplet and quadruplet regimens, into the management of patients with NDMM, Recommend appropriate antibody options for the management of RRMM, including for pat

Go online to PeerView.com/RVA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Improving outcomes for patients with advanced urothelial carcinoma (UC) has been challenging, with many patients experiencing only short periods of progression-free survival after treatment with first-line chemotherapy. A game changer in many cancers, immunotherapy has provided new avenues for the cancer care team to help their patients with advanced UC live longer. In particular, new data on the use of immunotherapy in the first-line maintenance setting has shown that using immunotherapy before patients’ progress to the second-line setting increases survival without a negative impact on quality of life. In this activity, a panel of experts discusses strategies for incorporating these important data into individualized patient care. Upon completion of this CE activity, participants will be able to: Cite the available clinical evidence on the use of immune checkpoint inhibitors a

Go online to PeerView.com/WXQ860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in infectious diseases discusses using telehealth to provide care to patients with HIV. Upon completion of this CE activity, participants should be better able to: Discuss how telehealth is transforming access to quality care and treatment for people with HIV during the coronavirus pandemic, Outline the telehealth technical resources available to manage patients living with HIV, Identify opportunities and strategies to leverage existing resources and infrastructure development to support the extension/utilization of telehealth, services by the healthcare team to provide HIV care.

Go online to PeerView.com/YQK860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in hematology-oncology provides an overview of paroxysmal nocturnal hemoglobinuria (PNH) and discusses current and emerging treatment options for managing PNH. Upon completion of this CE activity, participants will be able to: Discuss the complement pathway and its mechanistic relationship to paroxysmal nocturnal hemoglobinuria (PNH), Summarize efficacy and safety data surrounding complement pathway inhibitors, including factor B inhibitors, to treat PNH, Manage the unique adverse events associated with complement pathway inhibitors for PNH.

Go online to PeerView.com/TTU860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in psychiatry discusses the evidence for the use of GABA-modulating neuroactive steroids for major depressive disorder. Upon completion of this CE activity, participants will be able to: Summarize the evidence supporting a role for GABAergic dysfunction and altered neuroactive steroid signaling in major depressive disorder (MDD), Recognize the burden of MDD and the impact of delayed or suboptimal treatment on patient outcomes, Evaluate recent safety and efficacy data related to emerging treatment options for MDD, recognizing potential implications for the future treatment landscape.

Go online to PeerView.com/GWN860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The transformation of patient care in diffuse large b-cell lymphoma (DLBCL), driven by advances with antibodies and cellular therapy, continues—what will this mean for your practice? Find out in PeerView’s “Clinical Consults” video activity where a panel of DLBCL will focus on the applications of these dual innovations in the management of DLBCL. Using a series of alternating case-based discussions and mini-lectures, the panelists use recent science to explore the practice of novel antibodies and CAR-T cell therapy, including: the identification of candidates for treatment with novel antibodies or cellular therapy; the principles of therapeutic sequencing; appropriate safety management and monitoring strategies; and the emergence of novel immunotherapy options in the form of bispecific antibodies. Upon completion of this CE activity, participants will be able to: Summarize the t

Go online to PeerView.com/YVS860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Hyperkalemia is a potentially life-threatening condition caused by the inability of the kidneys to excrete potassium sufficiently. Excessive potassium levels can lead to cardiac arrhythmias and sudden cardiac death. Hyperkalemia is often encountered in hospitalized patients and frequently recurs after discharge. The problem is further complicated by the fact that guideline-directed medical therapies frequently used to reduce cardiorenal risks in patients with heart failure (HF) or chronic kidney disease (CKD) can increase the risk of hyperkalemia. Newer potassium binders may allow these patients to better tolerate guideline-directed therapies, as well as reduce the risk of hyperkalemia recurrence. Interprofessional models of care, such as those involving the pharmacist in transition-of-care interventions, have also been shown to improve patient outcomes. In this activity, based

Go online to PeerView.com/AGM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The orally bioavailable CDK4 and 6 inhibitors—abemaciclib, palbociclib, and ribociclib—have been established standard-of-care options in HR+/HER2- metastatic breast cancer for a while, and recently, abemaciclib was also approved in the adjuvant setting for the treatment of patients with early breast cancer (EBC) at high risk of early recurrence. This brings new hope to a group of patients with EBC who have been underserved by existing therapeutic options and have faced an unacceptably high risk of recurrence. With great progress in clinical research come questions about how to translate it into improvements in clinical practice. Which patients are/are not candidates for adjuvant CDK4 and 6 inhibition based on the recent FDA approval and updated ASCO recommendations? What is the role of Ki-67 testing in determining patient eligibility for treatment? How should risk be assessed to

Go online to PeerView.com/MVH860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in SSc-ILD discuss how to accurately interpret HRCT patterns, the latest diagnosis and management guidelines, including the importance of identifying and treating comorbidities, and the efficacy and safety of novel and emerging therapies. Upon completion of this CE activity, participants will be able to: Recognize signs, symptoms, and HRCT patterns indicative of ILD in patients with SSc and the importance of regular pulmonary monitoring in patients with SSc, Employ the latest guideline recommendations to the diagnosis and management of SSc-ILD in the context of an interprofessional approach, Apply the latest clinical evidence regarding efficacy and safety on novel and emerging therapies, including antifibrotic agents, to the treatment of SSc-ILD, Discuss the importance of assessing and managing comorbidities, such as gastroesophageal reflux disease and

Go online to PeerView.com/CMX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in sickle cell disease discuss current and future disease management strategies, including recent safety, efficacy, and tolerability data for currently approved and emerging therapies. Upon completion of this CE activity, participants will be able to: Discuss the disease burden, etiopathogenesis, complications, and unmet needs associated with SCD, Appraise recent safety, efficacy, and tolerability data associated with currently approved and emerging therapies for SCD including anti-adhesion agents, antisickling agents, and pyruvate kinase-R (PKR) activators among others, Develop treatment plans to prevent and/or reduce veno-occlusive crises and end-organ damage in patients with SCD, Implement collaborative strategies and shared decision-making practices to ensure patient engagement in treatment decisions and management of therapy-related adverse events.

Go online to PeerView.com/FTS860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This activity has been designed to meet the educational needs of gastroenterologists (pediatric and adult), allergists/immunologists (pediatric and adult), nurses, NPs, PAs, and other clinicians involved in the management of EoE. Upon completion of this CE activity, participants will be able to: Distinguish signs and symptoms of eosinophilic esophagitis (EoE) among children and adults to enable an earlier diagnosis and minimize complications due to uncontrolled disease, Summarize underlying mechanisms of EoE, including the role of key cytokines such as interleukin-4, -13, and -5 as drivers of type 2 inflammation and how this relates to potential treatment, Review the limitations of the current standard of care for the treatment of EoE, Apply the latest expert recommendations and clinical evidence to the treatment of patients with EoE, particularly as novel and emerging agents be

Go online to PeerView.com/HCA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in breast cancer discuss the latest advances in the management of patients with estrogen receptor–positive (ER+)/human epidermal growth factor receptor 2–negative (HER2-) breast cancer, including the rapidly accumulating evidence supporting the use of novel therapies such as selective estrogen receptor degraders (SERDs), selective estrogen receptor modulators (SERMs), selective estrogen receptor covalent antagonists (SERCAs), complete estrogen receptor antagonists (CERANs), and proteolysis-targeting chimeras (PROTACs), among others. In addition to analyzing the recent data from clinical trials with these ER-targeted therapies, patient case scenarios are presented to illustrate their potential role and use, and how to incorporate these novel treatments into the current management paradigm to improve outcomes in patients with ER+ breast cancer. Upon compl

Go online to PeerView.com/TCX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Hypertrophic cardiomyopathy (HCM) is a clinically complex disease that is often undiagnosed or misdiagnosed. The mechanisms behind its pathophysiology are not yet fully understood, but HCM has multiple underlying drivers, including cardiac muscle hypercontractility. It is the most common genetic heart disease and follows an autosomal dominant pattern with a poorly defined prevalence, age-dependent penetrance, and widely variable outcomes, as no medications are specifically indicated for its treatment. Encouragingly, recent advances in precision medicine and emerging treatment strategies, such as targeted therapy with small molecules, have demonstrated improvements in imaging parameters and quality of life. In this engaging activity, based on a recent live web broadcast, leading experts examine the pathophysiology of HCM, current guideline recommendations, and patient-centered ca

Go online to PeerView.com/EWB860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. How do your colleagues incorporate the latest research and guideline recommendations into the clinical management of patients with glioblastoma multiforme (GBM)? With a median overall survival of only 15 months, GBM has long presented a challenge to the multidisciplinary management team. To maximize patient survival and QOL, clinicians who treat patients with this complex, diverse, fast-growing, and aggressive brain tumor must be prepared to quickly create personalized management plans that incorporate several new modalities, including tumor treating fields (TTFields) and efficacious systemic therapies, as well as clinical trial–based options. In a new event from PeerView and the American Brain Tumor Association (ABTA), an expert panel will review the latest efficacy and safety data on multimodal GBM treatments, along with a clear rationale for selecting guideline-recommended tr